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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e33e8ef9ddf83c522418d8d5213093a38fa33275a6ad977ca3f3307500205523' 
  AND token = 'sRkb4BW32FvtOwf+ENxDmauWK7CJkb6prDvnVGvR9Zc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}