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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6eebfe763f6f890da1c049493e86654d22499471bb2964b4116cf245b1483382' 
  AND token = 'Ta4J0FEPlDqQr5d6PnL7v6/FMfoneaTE/bxwAwwIlXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}