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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75f864fac319e2575f026c9dd110ba55a050283101bc456d36e24161802b56e2' 
  AND token = 'BhNz65cGhLiH8Ar55bEI9dc+uBVdBt9YdvtGSqX11Xk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}