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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e1c261fd2bc6d43e47db2a7defc6ee0ee2848f4db4365cb0afc57034817578b' 
  AND token = 'QxVaRzDF9e6GXEBkLzL/Rd/BgI3QqQ8WUEDrtrLAPDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00134

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}