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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa4d9bd133e01e42d8884a5b3233743bf32907106e39ffded419b0e10dff15c3' 
  AND token = 'aPHFuud+VcGo7RJTFKGtyHKQo+r51RCd56n0JxRC6jg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}