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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '736cce3fb3d684b060d764e28b14cbca60f8142adacb7a82852e070e20d6b308' 
  AND token = 'ThVJgzbTT4wpWjaYCCTkw13vf63gdQFKZyP+NunopqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}