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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d24af839ad6d4caf20e7c59a77811c5dcbbc39b6f177d7753ca989becacff85' 
  AND token = 'sxYjES8T2NZv3gU3mifZ6A+s90Zvn3uDfs+AvOPbL2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}