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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9729f8a1724d07fa451144f13b926cbb076cc3e114f358d3eb6a6a2bb1fbddba' 
  AND token = 'ek889qHQnxu8wAxeJYHsBMya0BTawl7OvgGY5BIl30Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}