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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4982a20b229dea42a3c555201acb048c9aec944c10b84df1527d183bcf5bfbf' 
  AND token = 'M2m3tO5CLhvPY/OXKpSFRfIuptDam9tgw7oEQSm2gIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}