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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d2a63f20a54b39b1c051f0db647d6e8f04930fb4180bc95f144ae2149fdab10' 
  AND token = 'Nsk3eODbaZgzcZR2FB/utk5uan0r4W6uz3hHtB6Rlxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}