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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c66a2e6d5f521a4f3560089baaa4e3648bddb1ed90beeda66d4c5540e29e2b64' 
  AND token = 'yEiyCvIvU7wh22Q077VrRzLt8mTlEOJ/CBeRXaqigjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}