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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8491171eea105d558f1690b7424712677499c6c99dc3d2c2e68d68a9b497765c' 
  AND token = '+4fX6zp3HRraVIGJ2I4o9Hlcs7ZMIjGAlw47jsDQ090=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}