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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95d81faccd037b317fa2c1e37f563e8ed8cb48c7e0800e459a590bf95bb4ddaa' 
  AND token = 'e3B+Bm6DTTma+mtyQumcfB3ATrlTrnVwRyRsKZ0QnwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}