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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '887b5cffa14160c7f8fd4b4b8c09c99bbf53486ee47cb3b084d61324acfef56b' 
  AND token = 'ZFRENg2jtn8getVhIsgipkNjMpNUIYCxUC7rP+XxYL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}