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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cca3216d73f1fc149dd9d9d8be611968f2d3b4206fd24428da7f0cf17fa58d62' 
  AND token = 'QfMBarfbDyGGrAwQk6hyTEEenC+NotzlOAgyF9dQlIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}