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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2e3bfa2b84e4707051ded99a327df0459d7a59ff2b08fec2c40fb6177473247' 
  AND token = 'cHOhGmuuaDQS3Q9RNm3fFSYToeXD5e7p2V8SJtgpPPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}