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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16c943a60ee02a0c65de2d7706d34fb9aea35f9b5d0a86e418c44b7b9bef3354' 
  AND token = 'd3MJmE+f4tlDeaHEyDF1ywv1MBLdAH1vJCST9pLZjzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}