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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1095d3e116a01691157ee0a0cda29e90353ff2543fe92925ef3d01e9d34e4773' 
  AND token = 'F9GGh3ePF4NFT6+pcJZ3VB/2cbMjEPdFUFI5adXyB68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}