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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e48ed220f6444d432eb4bc94675a6c62b1ebb4aeea8b0243d7d1e8a165c39b4' 
  AND token = '2toApgAhvkflioiQn5mjyEi4uGA3iNN2I0vpPNtZH4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}