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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47d45b5b4e378f626b695282023e0b9a71a2f4dd287de8c18f0741d905b8c99c' 
  AND token = 'p0/1dilfkZzPGGCxrQNoInfS41zsCD2B4Ffs0/v+/YA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}