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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40d1c8a72a2bfe3e115d79ff37d99ba57704b21b3e06dadffe2c3d98959007c0' 
  AND token = 'ypFSc1G4/SrTEnHHykxOwrY6lIL9aVYwwjVF/jZJr0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}