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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7072a5019a40cdf577315c42793907d461c50b266d2fd70e4b692b0676a5ed1a' 
  AND token = '1XguI2ZKqM2qz0rm9rtGQ+Q2VIeWPA5LXgDK79PzICo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}