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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5a9bb18704ed35a808466fbeca340971baf36721d2b532967d17c8ac2db4010' 
  AND token = 'qf80slw22mkBW/VM5AAfy9clIOd0aULshvRZWnNeH0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}