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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b204e5b6ed6f4e44a6d226bd76e491cd1e6e96c8134cb0169c45073dd1ba069' 
  AND token = 'mUY4X7jEHSmo3GCQpmnKA7krsIH5Gar+sR6d9bwPQvU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}