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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43f86d971ebddc227c68c26ccb0c061a7d5f16256a1bc5cd6aebb821385de092' 
  AND token = 'uyR1sBvlZUNhj9BRlxo1dz8wUoMy95YWMdRW9+tl/Xw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}