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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e72ce510efbd4b760e022ddf0a5fa70d1b904b0bcac90491ffc99e80abc0039c' 
  AND token = '6XLDY9TQNJHMojw0JRI+woJtWsuEKdCS3OZq2ftatR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}