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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5812c4a91a6ad51fcf9b0c518a8f48cead1e2be89e2526481ae9aa987107460f' 
  AND token = 'OLobc0+mMYJU83h6PfJamFakLz5acGQObomA4EN3iNk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}