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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5b1fd5c5df3d4d3a3f5aba7c3fa80dc0048ab5ef5867a979efed88b099f4806' 
  AND token = '6GHoOoIpmJUpAMqPEB5OQ42xkhkG7GHYcrmUA/nu3l4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}