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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1b85a94811b83aadf54519a143fdb8a33999402b1dc34501b4d7fb66253ce95' 
  AND token = '8F4DlDm1e1k3624bxRR2drELnXLVL6puuOyCHEop6ys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}