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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01c8cdd6f247a957377715f3fda1cc38a02c06f2520669e20832d3d3351c8e66' 
  AND token = 'rY0kG4PNEEK+rH3hmjN8DM279lVUacoMYMGmgXrg4kw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}