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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e717c3560e4265fa2d1c179a92227d5a402b8553166ba296bbf3255460e68a83' 
  AND token = 'W5WCCNUT6gMoaFqXhhj1aZAgpV/69Iqpba4UUwYiLbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}