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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f3d67bd75f6d33b47f910156c66e3a21fab7acbb252725bb3371b249cdadc78' 
  AND token = 'xtVynubj2tY3pLHzNMl+XvG+vYaIEdvCdwEMu2NVqls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}