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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1f3fde0fc049108eeb935a9c3f97680b4b6483b941655243c17110a4cc93f7f' 
  AND token = '2zI2vrAUhoSTN9B+ur3HTgkYT4fbQnbWcSm9htKINKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00094

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}