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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53ef5b3c5c33353a1c931e9bace8b72591a5643102acb5e6e1fb3d604993029a' 
  AND token = '5LRwze0/8Y8h7VDSIOos4iIUSDXaX/v/Ih4VDFN1fQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}