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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7d6db5c64239391e55bd0a1019a75b1776b297f379adfdb357fc74ab31423bb' 
  AND token = 'sbUxWBCKj3qLieX+d/zsYrXnm8+72YIPI0ymoWYXBl4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}