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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43208afc4087716be6fa993d4ca422198ced8d0c29dc9fb829c0129312843da1' 
  AND token = 'EKinnG/Mf5ZgtFrgP22WnXvivPk/MD/V/44jolm0iHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}