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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d9ccdbc464057be4cb982d4e4b2e32b4f29f999290e6f52e57db565a41808bf' 
  AND token = 'Q2o06Dt00s5IyKJVWzZ4M/XBs03n9mzpNzLzAFbGFx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}