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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c1bd805b8da888f59e4d319601e9d7007d03ea6b2e767731d328ed99f463d3f' 
  AND token = 'hI0IgDG9fC03XCMXiQFyy+dauBpq7nLjm3DxlL0Vass=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}