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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9541ac2a3dd4bcaf0af4bbb276980a593486835ba1e691203884f64bec7b086' 
  AND token = '+LE3LBfQ1oAY837uf6uqbTJnveKyh72mRNkzGRuGgNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}