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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a05fd7fcce022b0a8602cdca8f139ab8e964c748333f3cf5106493c7ff3eb4fe' 
  AND token = 'wuBPm/DBbv+tAoF+NeB2HbaVNOXBbWWL1PMRDbUKEHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}