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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b5b0efbd521b10c4b9ab832772346dc82f0c325477d70ecb63290dc2c9710de' 
  AND token = 'bFbi45Qhcr9Z7fJUBtvzEZOXg3V5h+Dr46gGvtFWjAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}