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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e7b1e45c2b9d0c906c9311d8fcf0fcb78db53a159dc296ba53db882a27d2a2d' 
  AND token = 'IvAa4gaj/1C3M5sksNTFL1+Mw18einPIT4yCaDwqDT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}