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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0376589db3c3ed01d05329f5be8789a59c68aa7331b0bfb4f727f8a7470f4b8b' 
  AND token = '82HD0gl2sB+Xgv2z4Wtxf0HJIbgIbj/iwaNWAsx1DMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}