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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57fb54ae9eacc059d92bfdde7766603b0409131ec71e3027c3e3ea849db8076e' 
  AND token = 'JswidN7bgejRKhnOs8PN0glQY59hSJC7TtXbc0O7Zgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}