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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '299598afbe56de1baf3f2127f3fead1d93dd779920629961162f4cbf65a936e6' 
  AND token = 'NhORRonch/t0dyZPlG9j+HI7KUZtYulRoJejLeQCKyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}