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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '499665ae1bd1e43aeb58e5b622bf86182a44ba7b35165d1d6fe14be7bf5d70c0' 
  AND token = 'IZE38WrlA3rbfvLRig77gJxOZhmgegVTVQ8ezUdYWzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}