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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e95342069fbb45d460b5e476fbd4dcee4e98009b58f89d91b6498bcea98f8c03' 
  AND token = 'YnzZIwbm5YDmbLaEfXtLY8+pkRyoMDTxGM7XNLHLoXw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}