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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05dacd6a86d2c7829e6d725df6cbb849e6ac09718ae5e28754f89a39b55c6648' 
  AND token = '+jvjM53hiCIA0B+p+nkeq6A9HGlXeyZNYNiRdXTG7iw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}