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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9714f7910fdaeba88e67a00d26d3a316c0b9a92e1559073941d7923b6569e81' 
  AND token = 'Mjcl8QpK0XRG9SvGs3rc+sE5MKWaLaRHWuRCIYTDxFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}