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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d52b619908efb57291305df247675d19643f4c0827d7c1aaba37b3515e63004' 
  AND token = 'U9Cm+xS3A2zMlaW2Z/JM94hh5QrwDHNZLmErk+vQf9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}